Man looking down at a scale, illustrating concerns about weight gain potentially associated with low testosterone levels.

Does Low Testosterone Cause Weight Gain?

Testosterone Therapy
Weight Loss
Aug 4th, 2025
1
Min Read

Article / Does Low Testosterone Cause Weight Gain?

Many men notice they begin gaining weight at a significantly higher rate as they age, even if their lifestyle remains largely unchanged. Suddenly, men may find that it’s harder to lose belly fat, build muscle, or keep energy levels up.

At first, it’s easy to chalk this change in body composition up to just the effects of getting older. However, there could be something deeper going on beneath the surface in your body.

Low testosterone is one of the most overlooked reasons why men gain weight, especially after 40.  Contrary to popular belief, testosterone is not just a sex hormone. It is a powerful metabolic regulator. When it drops too low, it can trigger changes in body composition, energy, mood, and fat storage, which diets or exercise alone may struggle to reverse.

In this guide, we’ll explore how testosterone impacts your body weight, the signs to watch for, and what you can do if your hormones are working against you, causing you to gain excess weight.

How Testosterone Impacts Weight

Testosterone affects virtually every system involved in how your body uses, stores, and burns energy. From your metabolism to your muscle mass, low testosterone (also called low T) has a ripple effect that can set the stage for stubborn weight gain.

Testosterone and Metabolism

Your metabolism—how efficiently your body converts food into usable energy—is largely influenced by hormone activity. Testosterone boosts the basal metabolic rate (BMR), meaning it helps your body burn more calories at rest. Higher testosterone levels are associated with more lean muscle, which is metabolically active tissue. More muscle equals a faster metabolism. (1)

When testosterone levels fall, however, that metabolic efficiency drops. The body burns fewer calories, even while you sleep. This change alone can contribute to slow and steady weight gain over time, especially around the midsection.

Muscle Mass vs. Fat Storage

Testosterone is anabolic, meaning it helps build and preserve muscle tissue. It encourages protein synthesis, supports workout recovery, and fuels physical performance.

Low testosterone, on the other hand, leads to muscle wasting (sarcopenia). Studies have shown that testosterone levels drop at a rate of around 1% per year after age 30. (2) As muscle breaks down, your body composition shifts: you lose lean mass and gain fat mass, and this process tends to accelerate as you get older.

Men with low testosterone often find that no matter how hard they lift or how well they eat, it’s hard to make real progress. The body is in a biologically resistant state—geared more toward storing fat than building muscle.

The Vicious Cycle

When left untreated, particularly in older men, low testosterone can easily create a downward spiral:

  • Lower T levels reduce muscle mass.
  • Less muscle slows down metabolism.
  • Slower metabolism leads to fat gain, especially visceral (belly) fat.
  • Increased fat produces more aromatase, which converts testosterone into estrogen.
  • In men with excess fat, more testosterone is converted to estrogen, potentially lowering overall testosterone levels and relatively raising estrogen levels.
  • Higher estrogen and lower testosterone may further disrupt healthy testosterone production due to hormonal feedback mechanisms. (3)

Once this loop starts, breaking out of it without hormone intervention can be incredibly difficult.

Signs Your Weight Gain Might Be Hormonal

So, how do you know if your weight gain is related to low testosterone? While only bloodwork can fully confirm it, certain physical and emotional patterns suggest hormones may be part of the issue.

Here are some common red flags to be on the lookout for:

  • Increased belly fat, particularly visceral fat, without significant changes to your diet or exercise routine.
  • Loss of muscle tone, making you feel softer or weaker despite consistent workouts.
  • Fatigue and low energy, making it harder to stay active or even motivated.
  • Mood swings, irritability, or low motivation, often alongside brain fog.
  • A broader symptom cluster, such as thinning hair, problems sleeping, reduced libido, and/or erectile dysfunction, and weight gain.

One symptom alone isn’t necessarily cause for concern, and many of the issues above do happen naturally as you age. However, when several of these appear together, especially for men over 30, it may be pointing to a broader issue with your hormone health.

Other Factors That Contribute to Weight Gain

While low testosterone plays a significant role for many men, it’s important to acknowledge that weight gain is a multifactorial issue. Other factors, such as lifestyle choices, stress, diet, and other health conditions often work in tandem with hormonal imbalances to contribute to weight gain in men.

Consider these common contributors:

  • Diet and exercise: A caloric surplus combined with limited physical activity will eventually cause weight gain, regardless of testosterone levels. Low T can also lead to a lack of energy and motivation, which can cause you to skip workouts or abandon your diet.
  • Stress and poor sleep: Chronic stress raises cortisol levels, which encourages fat storage and disrupts testosterone production. (4) Sleep deprivation has similar effects—lowering testosterone, increasing cravings, and impairing recovery.
  • Aging and activity decline: As men get older, natural decreases in activity and recovery can slow down metabolism and change body composition.
  • Medication and medical conditions: Studies have shown that certain drugs such as several diabetes medications (including insulin and sulfonylurea), antihypertensive drugs, beta-blockers, calcium channel blockers, and psychotropic medications can have an effect on weight gain. (5)

    Additionally, certain medical conditions like thyroid disorders and insulin resistance can interfere with weight regulation and hormone production.

Because many of these issues share overlapping symptoms with low testosterone, it’s essential to work with a trusted provider, such as those at your local Gameday Men’s Health clinic, who can run accurate diagnostics and properly interpret your results in context.

How to Know If Low Testosterone Is the Cause

So how can you tell if low T is behind your new weight gain? The process starts with a clinical assessment that includes both symptom review and lab testing.

A testosterone panel typically includes several key components. First, it measures total testosterone, which reflects the overall level of the hormone in your blood. It also looks at free testosterone—the active, unbound form that your body can use immediately.

In some cases, providers will test for additional markers like estradiol, luteinizing hormone (LH), sex hormone-binding globulin (SHBG), or thyroid hormones to give a more comprehensive understanding of your hormonal health. These results, interpreted alongside your symptoms and medical history, can help determine whether low testosterone is contributing to your weight gain.

At Gameday Men’s Health, values are reviewed alongside your symptoms, lifestyle, and medical history. This helps rule out other causes and can determine whether testosterone replacement therapy (TRT) could be a safe and effective solution.

When it comes to low T, self-diagnosis and online quizzes won’t get you the results you need. Diagnosis and proper treatment from a trusted medical professional is essential.

Can Treating Low Testosterone Help with Weight Loss?

TRT is a medically supervised treatment that is designed to bring your testosterone levels back into a healthy, optimal range, which can vary. When it comes to weight gain, TRT has been shown to increase lean body mass and reduce fat mass, providing a pathway to substantial weight loss for eligible men. (6)

One study showed that, over a 56-week study of 100 obese men on a reduced calorie diet, men who received testosterone injections improved weight loss by 6.4 pounds over men who received no such treatment. (7)

While TRT isn’t a magic pill, it can restore the biological conditions that make fitness goals achievable again. In addition to reducing fat mass, TRT can also rev up your metabolic rate and improve motivation and stamina. This, in turn, can make exercise and healthy eating easier and more sustainable over the long-term.

Of course, TRT works best when paired with smart lifestyle choices. Think of it as removing a heavy roadblock—not replacing the road entirely. If you’re ready to explore treatment, learn more about our Testosterone Health Services and use our Location Finder to connect with a clinic near you.

Why Choose Gameday Men’s Health?

At Gameday Men’s Health, we specialize in hormone optimization and men’s health—because you deserve care that understands your body, your goals, and your challenges.

Here’s what sets us apart:

  • Hormone-focused care backed by expert providers who specialize in testosterone and men’s wellness.
  • Fast and accurate testosterone testing, done on-site in a private, comfortable setting catered towards men.
  • Tailored treatment plans designed to support your personal goals, whether you’re looking to lose weight, improve energy, or feel like yourself again.

We understand that unexplained weight gain can feel frustrating and discouraging. If you’re doing everything “right” and still not seeing results, don’t ignore the possibility that your hormones might be holding you back.

At Gameday Men’s Health, we help men take back control of their health, starting with answers and leading to action.  Whether you’re dealing with stubborn weight gain, low energy, or just haven’t been feeling like yourself, it’s time to make a change. Book a testosterone evaluation now at your local Gameday clinic to begin your journey to a healthier, happier you.

Testosterone Cypionate

Testosterone Cypionate provides long-acting hormone support through periodic injections that maintain steady testosterone levels. This option enhances muscle strength, bone health and overall vitality. Beneficial for men with confirmed hormone deficiency and performance-focused goals.

Read More...
SEE TREATMENT
SEE TREATMENT

Oral TRT (KYZATREX®)

This bioidentical oral testosterone formulation delivers stable hormone levels designed to restore energy, mood and masculine performance. It’s an ideal option for men seeking the convenience of a pill with the clinically proven benefits of medically supervised testosterone replacement.

Read More...
SEE TREATMENT
SEE TREATMENT

Testoterone Pellets

Testosterone pellets offer a slow-release solution for consistent hormone balance over months at a time. Once implanted beneath the skin, these pellets provide steady testosterone delivery, reducing the need for frequent dosing and helping men maintain energy, mood and drive with minimal disruption.

Read More...
SEE TREATMENT
SEE TREATMENT

Sermorelin

Sermorelin stimulates your body’s natural growth hormone production, supporting lean muscle growth, enhanced recovery, improved sleep and greater vitality. Ideal for men seeking a restorative, lifestyle-focused approach to aging well and maintaining energy, strength and overall wellness.

Read More...
SEE TREATMENT
SEE TREATMENT

Tirzepatide

Tirzepatide is a dual-action metabolic therapy that supports weight control by improving insulin sensitivity, reducing appetite, and enhancing satiety.
It helps regulate blood sugar levels and supports steady fat loss when combined with proper nutrition and lifestyle habits. This option is ideal for men seeking a guided, medically supervised approach to sustainable weight-management results.

Read More...
SEE TREATMENT
SEE TREATMENT

GLP-1 Therapy

GLP-1 therapy supports appetite regulation and blood sugar control to help men achieve steady, sustainable weight loss and improved metabolic health. For men who have tried diet and exercise yet still struggle with excess weight or energy dips, GLP-1 offers a medically-supervised option that aligns with performance, wellness and hormonal balance.

Read More...
SEE TREATMENT
SEE TREATMENT

SHOCKWAVE therapy

Shockwave therapy, also known as GainsWave®, uses low-intensity acoustic waves to stimulate new blood vessel growth and tissue regeneration. It’s a safe, non-invasive treatment that improves erectile function, sensation, and long-term performance without medication.

Read More...
SEE TREATMENT
SEE TREATMENT

Vitamin B12 injections

Vitamin B12 injections help boost energy, improve focus and support metabolic health by delivering a potent dose of this essential nutrient directly into your bloodstream. At Gameday we use B12 to support red blood cell and nerve health in men who feel fatigued or need a reliable vitality boost.

Read More...
SEE TREATMENT
SEE TREATMENT

MIC Lipotropic Injections

MIC Lipotropic injections deliver key nutrients designed to support fat metabolism, improve liver function and enhance overall energy. Ideal for men who train hard, travel often or need an extra metabolic boost, this therapy complements your lifestyle and helps your body make the most of your effort.

Read More...
SEE TREATMENT
SEE TREATMENT

P-Shot®

P-Shot® uses your body’s platelet-rich plasma to repair tissue, enhance blood flow, and increase sensitivity. This regenerative therapy supports stronger, longer-lasting erections while improving overall penile health and performance naturally.

Read More...
SEE TREATMENT
SEE TREATMENT
Fit man holding a Clomid pill bottle, highlighting treatment options for boosting testosterone and supporting men’s wellness.Fit man holding a Clomid pill bottle, highlighting treatment options for boosting testosterone and supporting men’s wellness.

Don’t just read about it, feel the difference.

Thousands of men have already taken the first step toward stronger energy, better performance, and lasting confidence. The science is real — and the results speak for themselves. Ready when you are.

Related Articles

A man running toward the future with the years 2024, 2025, and 2026 on the road, symbolizing progress in testosterone therapy as he moves toward improved health supported by a TRT clinic.

Kickstart 2026 Wellness: Elevate Men's Health with Gameday

As the new year approaches, focus on setting meaningful health goals. Embrace personalized wellness plans to unlock your best self and achieve optimal performance in 2026.
Read article
Read article
A man happily standing on a mountain peak, symbolizing renewed confidence and a fresh start thanks to effective ED treatment options for 2026.

Erectile Dysfunction Treatment Options to Start 2026 on a High Note

Explore the best erectile dysfunction treatment options for 2026, including medications, TRT, shockwave therapy, peptides, and more. Learn how to choose the right plan.
Read article
Read article
Man and woman smiling while lying on a bed, representing improved intimacy through natural ED treatments.

Natural Treatment for Erectile Dysfunction: What Works and What Doesn’t

Explore the best natural treatments for erectile dysfunction, including diet, exercise, supplements, stress reduction, and more. Learn when natural remedies help — and when to see a professional.
Read article
Read article
A man sits with a smile while two healthcare professionals discuss treatment options on a tablet, highlighting the personalized care and attention in choosing a testosterone replacement therapy clinic.

Your Health Matters: Choosing a Testosterone Replacement Therapy Clinic

Have you been feeling tired, find it difficult to sleep, or have a low sex drive? For many men in their late 30s and older, these can be common symptoms associated with low testosterone levels. Also known as low T, this hormonal imbalance can impact several important aspects of your health and your life.
Read article
Read article
A close-up of unhealthy foods like fried chicken, burgers, and sugary drinks that contribute to poor blood circulation and worsen erectile dysfunction symptoms in men.

Worst Foods for Erectile Dysfunction: What to Avoid for Better Performance

Learn which foods can worsen erectile dysfunction. Discover how diet affects blood flow, hormone balance, and performance — and what to eat instead.
Read article
Read article
Man at desk smiling while on phone with notepad in hand.

Why Office Workers Trust Gameday for Testosterone Therapy

Testosterone therapy can help office workers combat symptoms of low testosterone caused by sedentary lifestyles. Learn how it boosts energy, mood, and performance.
Read article
Read article
A muscular man preparing a testosterone injection, representing the importance of safe, medically supervised testosterone replacement therapy.

Why Is Testosterone a Controlled Substance? Understanding the Law and Safety

Learn why testosterone is a controlled substance, how it’s regulated, and why medical supervision is essential for safe and legal TRT.
Read article
Read article
Military man in casual wear relaxing on couch with dog in a warm, cozy room.

How Gameday’s TRT Empowers Military Members

Military personnel facing low testosterone can see improved strength, endurance, and mental sharpness through testosterone therapy. Understand its benefits and find tailored treatment options to boost performance and quality of life.
Read article
Read article
A young man sits on a bed, hand on head, reflecting on ED in young men, with a woman blurred in the background.

ED in Young Men: Overcoming Performance Anxiety and Regaining Confidence

For younger men experiencing ED, psychological factors can negatively impact sexual performance. Read about how to overcome performance anxiety in the bedroom.
Read article
Read article
Runner in a red jacket jogs through a snowy forest, an ideal scene for winter weight loss.

Unlock Winter Weight Loss with Gameday Men’s Health Solutions for Men

Winter weight gain is a common struggle for many men, but Gameday makes it easy to lose those stubborn pounds with personalized weight loss treatments.
Read article
Read article
Man in good shape stretching, highlighting fitness and weight loss benefits linked with GLP-1 treatments.

Which GLP-1 Is Best for Weight Loss?

GLP-1 medications have quickly become one of the most talked-about breakthroughs in medical weight loss. Originally developed for type 2 diabetes, these injectable treatments have recently been utilized to help patients shed significant weight while improving their metabolic health.
Read article
Read article
Two men stretching outdoors before a workout as a part of their weight loss journey combined with weight loss injections.

What is the Best Injection for Weight Loss? A Men’s Guide

For decades, the weight loss industry has pushed crash diets, endless cardio, and overpriced supplements. Most men who have struggled with weight loss have tried at least one of these “solutions,” only to watch the weight return over time. However, a new approach has been gaining attention in recent years: weight loss injections. When supported by clinical research and administered under medical supervision, these treatments are helping men lose fat more effectively than most fad diets ever could.
Read article
Read article